Investigating Sterol and Redox Regulation of the Ion Channel Activity of CLIC1 Using Tethered Bilayer Membranes

The Chloride Intracellular Ion Channel (CLIC) family consists of six conserved proteins in humans. These are a group of enigmatic proteins, which adopt both a soluble and membrane bound form. CLIC1 was found to be a metamorphic protein, where under specific environmental triggers it adopts more than...

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Bibliographic Details
Main Authors: Heba Al Khamici, Khondker R. Hossain, Bruce A. Cornell, Stella M. Valenzuela
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:Membranes
Subjects:
Online Access:http://www.mdpi.com/2077-0375/6/4/51