Detection of mixed populations of wild-type and YMDD hepatitis B variants by pyrosequencing in acutely and chronically infected patients

<p><b>Abstract</b></p> <p><b>Background</b></p> <p>Lamivudine (LAM) is associated with the highest known rate of resistance mutations among nucleotide analogs used to treat chronic hepatitis B virus (HBV) infection. Despite this, LAM continues in...

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Bibliographic Details
Main Authors: Mello Francisco C A, Lago Bárbara V, Lewis-Ximenez Lia L, Fernandes Carlos A, Gomes Selma A
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Microbiology
Online Access:http://www.biomedcentral.com/1471-2180/12/96