Recurrent, Severe Aphthous Stomatitis and Mucosal Ulcers as Primary Manifestations of a Novel STAT1 Gain-of-Function Mutation

Recurrent, Severe Aphthous Stomatitis and Mucosal Ulcers as Primary Manifestations of a Novel STAT1 Gain-of-Function Mutation

Chronic mucocutaneous candidiasis (CMC) characterized by persistent and recurrent Candida infection of the skin, nails, and the mucosa membranes has been proposed as the major infectious phenotype in patients with gain-of-function mutation of signal transducer and activator of transcription 1 (STAT1...

Full description

Bibliographic Details
Main Authors: Melinda Erdős, Eszter Jakobicz, Beáta Soltész, Beáta Tóth, Zsuzsanna Bata-Csörgő, László Maródi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
mucosal ulcers
STAT1
gain-of-function mutation
IL-17-mediated immunity
mucocutaneous candidiasis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00967/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00967/full

Similar Items