Immunogenicity and Efficacy of Live L. tarentolae Expressing KMP11-NTGP96-GFP Fusion as a Vaccine Candidate against Experimental Visceral Leishmaniasis Caused by L. infantum

Immunogenicity and Efficacy of Live L. tarentolae Expressing KMP11-NTGP96-GFP Fusion as a Vaccine Candidate against Experimental Visceral Leishmaniasis Caused by L. infantum

Background: The aim of present study was to evaluate the protective efficacy of live recombinant L. tarentolae expressing KMP11-NTGP96-GFP fusion as candidates for live engineered recombinant vaccine against visceral leishmaniasis in BALB/c mice. Methods: KMP-11 and NT-GP96 genes cloned into the p...

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Bibliographic Details
Main Authors: Vahid NASIRI, Abdolhossein DALIMI, Fatemeh GHAFFARIFAR, Azam BOLHASSANI
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2016-12-01
Series:Iranian Journal of Parasitology
Subjects:
KMP-11
NT-GP96
L. tarentolae
L. infantum
Visceral leishmaniasis
Vaccine
Online Access:https://ijpa.tums.ac.ir/index.php/ijpa/article/view/1054

Internet

https://ijpa.tums.ac.ir/index.php/ijpa/article/view/1054

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