A missense mutation in MYH1 is associated with susceptibility to immune-mediated myositis in Quarter Horses

A missense mutation in MYH1 is associated with susceptibility to immune-mediated myositis in Quarter Horses

Abstract Background The cause of immune-mediated myositis (IMM), characterized by recurrent, rapid-onset muscle atrophy in Quarter Horses (QH), is unknown. The histopathologic hallmark of IMM is lymphocytic infiltration of myofibers. The purpose of this study was to identify putative functional vari...

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Bibliographic Details
Main Authors: Carrie J. Finno, Giuliana Gianino, Sudeep Perumbakkam, Zoë J. Williams, Matthew H. Bordbari, Keri L. Gardner, Erin Burns, Sichong Peng, Sian A. Durward-Akhurst, Stephanie J. Valberg
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Skeletal Muscle
Subjects:
Equine
Genome-wide association
Immunology
Myopathy
Myosin heavy chain 1
Online Access:http://link.springer.com/article/10.1186/s13395-018-0155-0

Internet

http://link.springer.com/article/10.1186/s13395-018-0155-0

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