Genome-wide association study reveals multiple loci associated with primary tooth development during infancy.

Tooth development is a highly heritable process which relates to other growth and developmental processes, and which interacts with the development of the entire craniofacial complex. Abnormalities of tooth development are common, with tooth agenesis being the most common developmental anomaly in hu...

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Main Authors: Demetris Pillas, Clive J Hoggart, David M Evans, Paul F O'Reilly, Kirsi Sipilä, Raija Lähdesmäki, Iona Y Millwood, Marika Kaakinen, Gopalakrishnan Netuveli, David Blane, Pimphen Charoen, Ulla Sovio, Anneli Pouta, Nelson Freimer, Anna-Liisa Hartikainen, Jaana Laitinen, Sarianna Vaara, Beate Glaser, Peter Crawford, Nicholas J Timpson, Susan M Ring, Guohong Deng, Weihua Zhang, Mark I McCarthy, Panos Deloukas, Leena Peltonen, Paul Elliott, Lachlan J M Coin, George Davey Smith, Marjo-Riitta Jarvelin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2829062?pdf=render