<i>TYK2</i> Promoter Variant Is Associated with Impaired Insulin Secretion and Lower Insulin Resistance in Japanese Type 2 Diabetes Patients

<i>TYK2</i> Promoter Variant Is Associated with Impaired Insulin Secretion and Lower Insulin Resistance in Japanese Type 2 Diabetes Patients

Accumulating evidence has suggested that viral infection causes type 1 diabetes due to direct β-cell damage and the triggering of autoimmune reactivity to β cells. Here, we elucidated that the tyrosine kinase 2 <i>(Tyk2</i>) gene, encoding an interferon receptor signaling molecule, is re...

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Bibliographic Details
Main Authors: Hitoe Mori, Hirokazu Takahashi, Keiichiro Mine, Ken Higashimoto, Kanako Inoue, Motoyasu Kojima, Shigetaka Kuroki, Takahisa Eguchi, Yasuhiro Ono, Sadataka Inuzuka, Hidenobu Soejima, Seiho Nagafuchi, Keizo Anzai
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Genes
Subjects:
n/a
Online Access:https://www.mdpi.com/2073-4425/12/3/400

Internet

https://www.mdpi.com/2073-4425/12/3/400

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