Neuroplasticity induced by general anaesthesia: study protocol for a randomised cross-over clinical trial exploring the effects of sevoflurane and propofol on the brain – A 3-T magnetic resonance imaging study of healthy volunteers

Neuroplasticity induced by general anaesthesia: study protocol for a randomised cross-over clinical trial exploring the effects of sevoflurane and propofol on the brain – A 3-T magnetic resonance imaging study of healthy volunteers

Abstract Background Although used extensively worldwide, the effects of general anaesthesia on the human brain remain largely elusive. Moreover, general anaesthesia may contribute to serious conditions or adverse events such as postoperative cognitive dysfunction and delirium. To understand the basi...

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Bibliographic Details
Main Authors: Signe Sloth Madsen, Kirsten Møller, Karsten Skovgaard Olsen, Mark Bitsch Vestergaard, Ulrich Lindberg, Henrik Bo Wiberg Larsson, Johan Mårtensson, Mads U. Werner, Sofia Alexandra Gaspar Santos, Mohammad Sohail Asghar
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Trials
Subjects:
Neuroplasticity
Neuroplastic changes
General anaesthesia
Magnetic resonance imaging
Sevoflurane
Propofol
Online Access:http://link.springer.com/article/10.1186/s13063-020-04468-y

Internet

http://link.springer.com/article/10.1186/s13063-020-04468-y

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