The Effects of Lyophilization on the Physico-Chemical Stability of Sirolimus Liposomes

Purpose: The major limitation in the widespread use of liposome drug delivery system is its instability. Lyophilization is a promising approach to ensure the long-term stability of liposomes. The aim of this study was to prepare sirolimus-loaded liposomes, study their stability and investigate the e...

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Bibliographic Details
Main Authors: Parvin Zakeri-Milani, Hadi Valizadeh, Saeed Ghanbarzadeh
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2013-02-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:http://journals.tbzmed.ac.ir/PDF/APB/Manuscript/APB-3-25.pdf