Sm10.3, a member of the micro-exon gene 4 (MEG-4) family, induces erythrocyte agglutination in vitro and partially protects vaccinated mice against Schistosoma mansoni infection.

BACKGROUND: The parasitic flatworm Schistosoma mansoni is a blood fluke that causes schistosomiasis. Current schistosomiasis control strategies are mainly based on chemotherapy, but many researchers believe that the best long-term strategy to control disease is a combination of drug treatment and im...

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Bibliographic Details
Main Authors: Vicente P Martins, Suellen B Morais, Carina S Pinheiro, Natan R G Assis, Barbara C P Figueiredo, Natasha D Ricci, Juliana Alves-Silva, Marcelo V Caliari, Sergio C Oliveira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3961193?pdf=render