Predictive model of asthma formation in children with atopic dermatitis

• Main Authors: S. V. Levasheva, E. I. Etkina, L. L. Guryeva, A. R. Biktasheva, S. E. Yakuta, L. Y. Danilova
• Format: Article
• Language: Russian
• Published: Remedium Group LLC 2016-12-01
• Series: Медицинский совет
• Subjects: atopic dermatitis; bronchial asthma; children; logistic regression
• Online Access: https://www.med-sovet.pro/jour/article/view/1268

One of the highest risk factors for bronchial asthma (BA) in children is atopic dermatitis (AD). In this regard, current research is aimed at identifying additional predictors of asthma in the population of patients with AD. Aim: to develop a mathematical model for predicting the risk of BA in children with AD. Material and methods: 315 children aged 0 to 18 years were examined, of which 138 with AD and no BA and 177 with AD and BA. Logistic regression method was used for the development of the mathematical model. Results: based on the obtained data, logistic regression equation with 7 predictors was chosen (age; intrauterine infection; pneumonia, acute obstructive bronchitis and chronic adenoids over the age of two; allergic diseases of the father and mother’s relatives) the statistical significance of which was within 5% Wald test.