Inhibited Dopamine Synthesizing Cell Model of AADC Deficiency

Introduction: Aromatic L-amino acid decarboxylase deficiency (AADC) is a rare autosomal recessive pediatric neurotransmitter disease. To date it remains poorly understood mainly due to an absence of a disease model. The dopaminergic neuroblastoma cell SH-SY5Y was chosen to develop our AADC deficienc...

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Bibliographic Details
Main Authors: Melati Khalid, Mohamad Aris Mohd Moklas
Format: Article
Language:English
Published: Biome Scientia 2019-06-01
Series:Life Sciences, Medicine and Biomedicine
Subjects:
Online Access:http://biomescientia.com/index.php/lsmb/article/view/24