Preparation and activity of glycosylated acetylsalicylic acid

Preparation and activity of glycosylated acetylsalicylic acid

The glycosylated acetylsalicylic acid was prepared with bromo-α-d-galactose and acetylsalicylic acid. It indicated that the glycosylated acetylsalicylic acid had lower cytotoxicity than underivatized acetylsalicylic acid, and might selectively display anticancer activity in this situation that had e...

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Bibliographic Details
Main Authors: Gangliang Huang, Hao Cheng, Yang Liu, Jinchuan Hu
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Saudi Pharmaceutical Journal
Subjects:
Acetylsalicylic acid
Glycosylated
Preparation
Cytotoxicity
Anticancer activity
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016417302098
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spelling doaj-3d81e52b586d4469a1bb6c8333f665022020-11-24T23:49:23ZengElsevierSaudi Pharmaceutical Journal1319-01642018-02-0126226326510.1016/j.jsps.2017.12.001Preparation and activity of glycosylated acetylsalicylic acidGangliang HuangHao ChengYang LiuJinchuan HuThe glycosylated acetylsalicylic acid was prepared with bromo-α-d-galactose and acetylsalicylic acid. It indicated that the glycosylated acetylsalicylic acid had lower cytotoxicity than underivatized acetylsalicylic acid, and might selectively display anticancer activity in this situation that had enzyme or no enzyme.http://www.sciencedirect.com/science/article/pii/S1319016417302098Acetylsalicylic acidGlycosylatedPreparationCytotoxicityAnticancer activity
collection DOAJ
language English
format Article
sources DOAJ
author Gangliang Huang
Hao Cheng
Yang Liu
Jinchuan Hu
spellingShingle Gangliang Huang
Hao Cheng
Yang Liu
Jinchuan Hu
Preparation and activity of glycosylated acetylsalicylic acid
Saudi Pharmaceutical Journal
Acetylsalicylic acid
Glycosylated
Preparation
Cytotoxicity
Anticancer activity
author_facet Gangliang Huang
Hao Cheng
Yang Liu
Jinchuan Hu
author_sort Gangliang Huang
title Preparation and activity of glycosylated acetylsalicylic acid
title_short Preparation and activity of glycosylated acetylsalicylic acid
title_full Preparation and activity of glycosylated acetylsalicylic acid
title_fullStr Preparation and activity of glycosylated acetylsalicylic acid
title_full_unstemmed Preparation and activity of glycosylated acetylsalicylic acid
title_sort preparation and activity of glycosylated acetylsalicylic acid
publisher Elsevier
series Saudi Pharmaceutical Journal
issn 1319-0164
publishDate 2018-02-01
description The glycosylated acetylsalicylic acid was prepared with bromo-α-d-galactose and acetylsalicylic acid. It indicated that the glycosylated acetylsalicylic acid had lower cytotoxicity than underivatized acetylsalicylic acid, and might selectively display anticancer activity in this situation that had enzyme or no enzyme.
topic Acetylsalicylic acid
Glycosylated
Preparation
Cytotoxicity
Anticancer activity
url http://www.sciencedirect.com/science/article/pii/S1319016417302098
work_keys_str_mv AT ganglianghuang preparationandactivityofglycosylatedacetylsalicylicacid
AT haocheng preparationandactivityofglycosylatedacetylsalicylicacid
AT yangliu preparationandactivityofglycosylatedacetylsalicylicacid
AT jinchuanhu preparationandactivityofglycosylatedacetylsalicylicacid
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