An evaluation on the activity level of Aspartate aminotransferase and Alkaline phosphatase nzymes in peri-implant sulcus fluid

Statement of Problem: The correlation between the activity of aspartate aminotransferase (AST) and alkaline phosphatase (ALP) enzymes in gingival sulcular fluid (GCF) with inflammation and periodontal attachment loss has been proved, however there are not adequate studies about dental implants. Purp...

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Main Authors: Paknegad M. Assistant Professor, Miremadi A. Associate Professor, Tabatabaei-e-Yazdi M. Associate Professor, Khodadad-e- Motarjemi M. Resident
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2003-07-01
Series:Journal of Dental Medicine
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4622.pdf&manuscript_id=4622
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spelling doaj-3da1da3af3084c3fa684242d6e634c412020-11-24T23:51:59ZfasTehran University of Medical SciencesJournal of Dental Medicine1024-641X2008-24442003-07-011626472An evaluation on the activity level of Aspartate aminotransferase and Alkaline phosphatase nzymes in peri-implant sulcus fluidPaknegad M. Assistant ProfessorMiremadi A. Associate ProfessorTabatabaei-e-Yazdi M. Associate ProfessorKhodadad-e- Motarjemi M. ResidentStatement of Problem: The correlation between the activity of aspartate aminotransferase (AST) and alkaline phosphatase (ALP) enzymes in gingival sulcular fluid (GCF) with inflammation and periodontal attachment loss has been proved, however there are not adequate studies about dental implants. Purpose: The aim of present study was to investigate the presence and activity level of AST & ALP and their correlation with pocket depth (PD) and bleeding of peri-implant slcular fluid (PISF), and to evaluate the possibility of using these assessments as a diagnostic index in oral implantology. Material and Methods: In this study, 41 implants as test group and 41 contralateral teeth as control group, in 21 patients were evaluated. At first visit, the general information about implants and the values of pocket probing depth (PPD), modified sulcus bleeding index (mSBl) and modified plaque index (mPI) were recorded. At the second visit, samples of GCF/PISF were collected. AST & ALP activity was determined spectrophotometrically and data were analyzed by "t", "Mann-Whitney" tests and Pearson Spearman correlation coefficient."nResults: The results showed that there was a significant difference in the activity of AST between two study groups (P<0.0001). The average activity of ALP in test group was more than control group but the difference was not significant. After elimination of the confounding variables, the average AST in test group was 54.6 (S£=2.3) and in control groups was 44.8 (SE=2.3) (P=0.004). The average ALP in test group (SE=2.2) and in control (SE=2.2) were 36.6 and 35.4, respectively. Values of AST and ALP were positively correlated with other clinical parameters such as PD and mSBI which was significant in test group."nConclusion: The present study suggests that PISF analysis could be considered as a proper diagnostic strategy in the evaluation of dental implant success.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4622.pdf&manuscript_id=4622Dental implants, Gingival crevicular fluidPeri-implant sulcus fluid
collection DOAJ
language fas
format Article
sources DOAJ
author Paknegad M. Assistant Professor
Miremadi A. Associate Professor
Tabatabaei-e-Yazdi M. Associate Professor
Khodadad-e- Motarjemi M. Resident
spellingShingle Paknegad M. Assistant Professor
Miremadi A. Associate Professor
Tabatabaei-e-Yazdi M. Associate Professor
Khodadad-e- Motarjemi M. Resident
An evaluation on the activity level of Aspartate aminotransferase and Alkaline phosphatase nzymes in peri-implant sulcus fluid
Journal of Dental Medicine
Dental implants, Gingival crevicular fluid
Peri-implant sulcus fluid
author_facet Paknegad M. Assistant Professor
Miremadi A. Associate Professor
Tabatabaei-e-Yazdi M. Associate Professor
Khodadad-e- Motarjemi M. Resident
author_sort Paknegad M. Assistant Professor
title An evaluation on the activity level of Aspartate aminotransferase and Alkaline phosphatase nzymes in peri-implant sulcus fluid
title_short An evaluation on the activity level of Aspartate aminotransferase and Alkaline phosphatase nzymes in peri-implant sulcus fluid
title_full An evaluation on the activity level of Aspartate aminotransferase and Alkaline phosphatase nzymes in peri-implant sulcus fluid
title_fullStr An evaluation on the activity level of Aspartate aminotransferase and Alkaline phosphatase nzymes in peri-implant sulcus fluid
title_full_unstemmed An evaluation on the activity level of Aspartate aminotransferase and Alkaline phosphatase nzymes in peri-implant sulcus fluid
title_sort evaluation on the activity level of aspartate aminotransferase and alkaline phosphatase nzymes in peri-implant sulcus fluid
publisher Tehran University of Medical Sciences
series Journal of Dental Medicine
issn 1024-641X
2008-2444
publishDate 2003-07-01
description Statement of Problem: The correlation between the activity of aspartate aminotransferase (AST) and alkaline phosphatase (ALP) enzymes in gingival sulcular fluid (GCF) with inflammation and periodontal attachment loss has been proved, however there are not adequate studies about dental implants. Purpose: The aim of present study was to investigate the presence and activity level of AST & ALP and their correlation with pocket depth (PD) and bleeding of peri-implant slcular fluid (PISF), and to evaluate the possibility of using these assessments as a diagnostic index in oral implantology. Material and Methods: In this study, 41 implants as test group and 41 contralateral teeth as control group, in 21 patients were evaluated. At first visit, the general information about implants and the values of pocket probing depth (PPD), modified sulcus bleeding index (mSBl) and modified plaque index (mPI) were recorded. At the second visit, samples of GCF/PISF were collected. AST & ALP activity was determined spectrophotometrically and data were analyzed by "t", "Mann-Whitney" tests and Pearson Spearman correlation coefficient."nResults: The results showed that there was a significant difference in the activity of AST between two study groups (P<0.0001). The average activity of ALP in test group was more than control group but the difference was not significant. After elimination of the confounding variables, the average AST in test group was 54.6 (S£=2.3) and in control groups was 44.8 (SE=2.3) (P=0.004). The average ALP in test group (SE=2.2) and in control (SE=2.2) were 36.6 and 35.4, respectively. Values of AST and ALP were positively correlated with other clinical parameters such as PD and mSBI which was significant in test group."nConclusion: The present study suggests that PISF analysis could be considered as a proper diagnostic strategy in the evaluation of dental implant success.
topic Dental implants, Gingival crevicular fluid
Peri-implant sulcus fluid
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4622.pdf&manuscript_id=4622
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