A critical role of Pax6 in alcohol-induced fetal microcephaly

Maternal alcohol abuse during pregnancy is one of the leading causes of birth defects in humans. Despite extensive studies, the molecular basis is still not clear. Here we transiently exposed Xenopus embryos to alcohol and showed that alcohol dose-dependently produced microcephaly and growth retarda...

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Bibliographic Details
Main Authors: Ying Peng, Pai-Hao Yang, Samuel S.M Ng, Oscar G Wong, Jie Liu, Ming-Liang He, Hsiang-Fu Kung, Marie C.M Lin
Format: Article
Language:English
Published: Elsevier 2004-07-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104000622