Gene Expression Signature Predictive of Neuroendocrine Transformation in Prostate Adenocarcinoma

Gene Expression Signature Predictive of Neuroendocrine Transformation in Prostate Adenocarcinoma

Neuroendocrine prostate cancer (NEPC) can arise de novo, but much more commonly occurs as a consequence of a selective pressure from androgen deprivation therapy or androgen receptor antagonists used for prostate cancer (PCa) treatment. The process is known as neuroendocrine transdifferentiation. Th...

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Bibliographic Details
Main Authors: Paola Ostano, Maurizia Mello-Grand, Debora Sesia, Ilaria Gregnanin, Caterina Peraldo-Neia, Francesca Guana, Elena Jachetti, Antonella Farsetti, Giovanna Chiorino
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
neuroendocrine prostate cancer
neuroendocrine transdifferentiation
prostate cancer
long non coding rnas
estrogen signaling pathway
predictive gene signature
Online Access:https://www.mdpi.com/1422-0067/21/3/1078

Internet

https://www.mdpi.com/1422-0067/21/3/1078

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