Male carriers of the FMR1 premutation show altered hippocampal-prefrontal function during memory encoding

Male carriers of the FMR1 premutation show altered hippocampal-prefrontal function during memory encoding

Previous functional MRI (fMRI) studies have shown that fragile X mental retardation 1 (FMR1) premutation allele carriers (FXPCs) exhibit decreased hippocampal activation during a recall task and lower inferior frontal activation during a working memory task compared to matched controls. The molecula...

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Bibliographic Details
Main Authors: John M Wang, Kami eKoldewyn, Ryu-ichiro eHashimoto, Andrea eSchneider, Lien eLi, Flora eTassone, Katherine eCheung, Paul eHagerman, David eHessl, Susan M Rivera
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Human Neuroscience
Subjects:
Hippocampus
fMRI
Fragile X premutation
Memory encoding
Psychological Interaction Analysis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2012.00297/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnhum.2012.00297/full

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