Surgical procedures suppress autophagic flux in the kidney

Abstract Many surgical models are used to study kidney and other diseases in mice, yet the effects of the surgical procedure itself on the kidney and other tissues have not been elucidated. In the present study, we found that both sham surgery and unilateral nephrectomy (UNX), which is used as a mod...

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Bibliographic Details
Main Authors: Carolyn N. Brown, Daniel Atwood, Deepak Pokhrel, Sara J. Holditch, Christopher Altmann, Nataliya I. Skrypnyk, Jennifer Bourne, Jelena Klawitter, Judith Blaine, Sarah Faubel, Andrew Thorburn, Charles L. Edelstein
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03518-w