Effects of freezing rate on structural changes in l-lactate dehydrogenase during the freezing process

Abstract Freezing is a common method for improving enzyme storage stability. During the freezing process, the freezing rate is an important parameter that can affect protein stability. However, there is limited information on the denaturation mechanisms and protein conformational changes associated...

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Bibliographic Details
Main Authors: Haena Park, Jun-Young Park, Kyung-Min Park, Pahn-Shick Chang
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93127-6