The in vivo genetic program of murine primordial lung epithelial progenitors

The in vivo genetic program of murine primordial lung epithelial progenitors

The identity of the earliest murine in vivo lung epithelial progenitors (marked by NKX2-1 expression) is unclear. Here, the authors use single-cell RNA sequencing to define the genetic program of these lung primordial progenitors, which will improve in vitro lung specification of pluripotent stem ce...

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Bibliographic Details
Main Authors: Laertis Ikonomou, Michael J. Herriges, Sara L. Lewandowski, Robert Marsland, Carlos Villacorta-Martin, Ignacio S. Caballero, David B. Frank, Reeti M. Sanghrajka, Keri Dame, Maciej M. Kańduła, Julia Hicks-Berthet, Matthew L. Lawton, Constantina Christodoulou, Attila J. Fabian, Eric Kolaczyk, Xaralabos Varelas, Edward E. Morrisey, John M. Shannon, Pankaj Mehta, Darrell N. Kotton
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14348-3

Internet

https://doi.org/10.1038/s41467-020-14348-3

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