Investigation of the effect of 5-Aza-2'-deoxycytidine in comparison to and in combination with trichostatin a on p16INK4a, p14ARF, p15INK4b gene expression, cell growth inhibition and apoptosis induction in colon cancer Caco-2 cell line

Background: The cell cycle is divided into four phases, G1, G2, S, and M phase. The mammalian cell cycle is controlled and governed by the kinase complexes including cyclin and the cyclin-dependent kinase (CDK), cyclin-CDK complexes. The activity of the complexes is regulated by cyclin-dependent kin...

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Bibliographic Details
Main Authors: Masumeh Sanaei, Fraidoon Kavoosi, Vahid Ghasemzadeh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:International Journal of Preventive Medicine
Subjects:
Online Access:http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2021;volume=12;issue=1;spage=64;epage=64;aulast=Sanaei