Epstein–Barr Virus Infection of Mammary Epithelial Cells Promotes Malignant Transformation

Whether the human tumor virus, Epstein–Barr Virus (EBV), promotes breast cancer remains controversial and a potential mechanism has remained elusive. Here we show that EBV can infect primary mammary epithelial cells (MECs) that express the receptor CD21. EBV infection leads to the expansion of early...

Full description

Bibliographic Details
Main Authors: Hai Hu, Man-Li Luo, Christine Desmedt, Sheida Nabavi, Sina Yadegarynia, Alex Hong, Panagiotis A. Konstantinopoulos, Edward Gabrielson, Rebecca Hines-Boykin, German Pihan, Xin Yuan, Christos Sotirious, Dirk P. Dittmer, Joyce D. Fingeroth, Gerburg M. Wulf
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416302092