Bioinformatic and mass spectrometry identification of Anaplasma phagocytophilum proteins translocated into host cell nuclei

Obligate intracellular bacteria have an arsenal of proteins that alter host cells to establish and maintain a hospitable environment for replication. Anaplasma phagocytophilum secrets Ankyrin A (AnkA), via a type IV secretion system, which translocates to the nucleus of its host cell, human neutroph...

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Bibliographic Details
Main Authors: Sara H. G. Sinclair, Jose Carlos Garcia-Garcia, J Stephen Dumler
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00055/full