Activation of the innate immune response against DENV in normal non-transformed human fibroblasts.

BACKGROUND:When mosquitoes infected with DENV are feeding, the proboscis must traverse the epidermis several times ("probing") before reaching a blood vessel in the dermis. During this process, the salivary glands release the virus, which is likely to interact first with cells of the vario...

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Main Authors: José Bustos-Arriaga, Jazmín García-Machorro, Moisés León-Juárez, Julio García-Cordero, Leopoldo Santos-Argumedo, Leopoldo Flores-Romo, A René Méndez-Cruz, Francisco J Juárez-Delgado, Leticia Cedillo-Barrón
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22206025/?tool=EBI