Co-expressing LRP6 With Anti-CD19 CAR-T Cells for Improved Therapeutic Effect Against B-ALL

Co-expressing LRP6 With Anti-CD19 CAR-T Cells for Improved Therapeutic Effect Against B-ALL

BackgroundCellular immunotherapies, such as chimeric antigen receptor modified-T cell (CAR-T) therapy, offers excellent potential for tumor treatment. The memory phenotype of CAR-T has been correlated positively with a therapeutic effect on and prognosis of cancer.MethodThe proliferation rates of no...

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Bibliographic Details
Main Authors: Ping He, Zhongqiu Tan, Zhongheng Wei, Cheng-Liang Wan, Shan-Shan Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
tumor immunotherapy
CAR-T cells
T memory cell
B-cell acute lymphocytic leukemia
tumor treatment
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01346/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.01346/full

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