Prospective multicenter evaluation of real time PCR Kit prototype for early diagnosis of congenital Chagas disease

Prospective multicenter evaluation of real time PCR Kit prototype for early diagnosis of congenital Chagas disease

Background: Current algorithm for Congenital Chagas Disease (cCD) diagnosis is unsatisfactory due to low sensitivity of the parasitological methods. Moreover, loss to follow-up precludes final serodiagnosis after nine months of life in many cases. A duplex TaqMan qPCR kit for Trypanosoma cruzi DNA a...

Full description

Bibliographic Details
Main Authors: Alejandro Francisco Benatar, Emmaría Danesi, Susana Alicia Besuschio, Santiago Bortolotti, María Luisa Cafferata, Juan Carlos Ramirez, Constanza Lopez Albizu, Karenina Scollo, María Baleani, Laura Lara, Gustavo Agolti, Sandra Seu, Elsa Adamo, Raúl Horacio Lucero, Lucía Irazu, Marcelo Rodriguez, Andrés Poeylaut-Palena, Silvia Andrea Longhi, Mónica Esteva, Fernando Althabe, Federico Rojkin, Jacqueline Bua, Sergio Sosa-Estani, Alejandro Gabriel Schijman
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:EBioMedicine
Subjects:
Congenital Chagas disease
Early diagnosis
Real Time PCR
Trypanosoma cruzi
Discrete typing unit
Parasitic load
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421002437

Internet

http://www.sciencedirect.com/science/article/pii/S2352396421002437

Similar Items