Silibinin suppresses epithelial–mesenchymal transition in human non-small cell lung cancer cells by restraining RHBDD1

Silibinin suppresses epithelial–mesenchymal transition in human non-small cell lung cancer cells by restraining RHBDD1

Abstract Background Rhomboid domain containing 1 (RHBDD1) plays a crucial role in tumorigenesis. Silibinin, which is a natural extract from milk thistle, has shown anti-tumor effects against various tumors. Here, we investigate whether silibinin affects the function of RHBDD1 in non-small cell lung...

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Bibliographic Details
Main Authors: Suyan Xu, Hongyan Zhang, Aifeng Wang, Yongcheng Ma, Yuan Gan, Guofeng Li
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Cellular & Molecular Biology Letters
Subjects:
NSCLC
Silibinin
RHBDD1
Epithelial–mesenchymal transition
Online Access:http://link.springer.com/article/10.1186/s11658-020-00229-6

Internet

http://link.springer.com/article/10.1186/s11658-020-00229-6

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