Exposome-wide association study of semen quality: Systematic discovery of endocrine disrupting chemical biomarkers in fertility require large sample sizes

Objectives: Exposome-wide association studies (EWAS) are a systematic and unbiased way to investigate multiple environmental factors associated with phenotype. We applied EWAS to study semen quality and queried the sample size requirements to detect modest associations in a reproductive cohort. Stud...

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Bibliographic Details
Main Authors: Ming Kei Chung, Germaine M. Buck Louis, Kurunthachalam Kannan, Chirag J. Patel
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Environment International
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412018319147