Effects of Androgen Receptor Inhibition on Kanamycin-Induced Hearing Loss in Rats

Effects of Androgen Receptor Inhibition on Kanamycin-Induced Hearing Loss in Rats

Megalin has been proposed as an endocytic receptor for aminoglycosides as well as estrogen and androgen. We aimed to investigate the otoprotective effects of antiandrogens (flutamide, FM) on kanamycin (KM)-induced hearing loss in rats. Rats were divided into four groups. The KM group was administere...

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Bibliographic Details
Main Authors: Kyung-Ju Chun, Chang-Ho Lee, Kyung-Woon Kim, So-Min Lee, So-Young Kim
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
receptors, androgen
aminoglycosides
hearing loss
low-density lipoprotein receptor-related protein-2
metallothionein
Online Access:https://www.mdpi.com/1422-0067/22/10/5307

Internet

https://www.mdpi.com/1422-0067/22/10/5307

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