Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008

Highland areas where malaria transmission is unstable are targets for malaria elimination because transmission decreases to low levels during the dry season. In highland areas of Kipsamoite and Kapsisiywa, Kenya (population ≈7,400 persons), annual household indoor residual spraying with a synthetic...

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Main Authors: Chandy C. John, Melissa A. Riedesel, Ng’wena G. Magak, Kim A. Lindblade, David M. Menge, James S. Hodges, John M. Vulule, Willis Akhwale
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2009-12-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/15/12/09-0627_article
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spelling doaj-43173867fd3e4641a95dda22b0db18842020-11-24T21:50:07ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592009-12-0115121917192410.3201/eid1512.090627Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008Chandy C. JohnMelissa A. RiedeselNg’wena G. MagakKim A. LindbladeDavid M. MengeJames S. HodgesJohn M. VululeWillis AkhwaleHighland areas where malaria transmission is unstable are targets for malaria elimination because transmission decreases to low levels during the dry season. In highland areas of Kipsamoite and Kapsisiywa, Kenya (population ≈7,400 persons), annual household indoor residual spraying with a synthetic pyrethroid was performed starting in 2005, and artemether/lumefantrine was implemented as first-line malaria treatment in October 2006. During April 2007–March 2008, no microscopy-confirmed cases of malaria occurred at the sites. In 4 assessments of asymptomatic persons during May 2007–April 2008, a total of <0.3% of persons were positive for asexual Plasmodium falciparum by microscopy or PCR at any time, and none were positive by PCR at the last 2 sample collections. Our findings show that in such areas, interruption and eventual elimination of malaria transmission may be achievable with widespread annual indoor residual spraying of households and artemisinin combination therapy.https://wwwnc.cdc.gov/eid/article/15/12/09-0627_articleMalariatransmissionPlasmodium falciparumepidemiologyKenyaparasites
collection DOAJ
language English
format Article
sources DOAJ
author Chandy C. John
Melissa A. Riedesel
Ng’wena G. Magak
Kim A. Lindblade
David M. Menge
James S. Hodges
John M. Vulule
Willis Akhwale
spellingShingle Chandy C. John
Melissa A. Riedesel
Ng’wena G. Magak
Kim A. Lindblade
David M. Menge
James S. Hodges
John M. Vulule
Willis Akhwale
Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008
Emerging Infectious Diseases
Malaria
transmission
Plasmodium falciparum
epidemiology
Kenya
parasites
author_facet Chandy C. John
Melissa A. Riedesel
Ng’wena G. Magak
Kim A. Lindblade
David M. Menge
James S. Hodges
John M. Vulule
Willis Akhwale
author_sort Chandy C. John
title Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008
title_short Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008
title_full Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008
title_fullStr Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008
title_full_unstemmed Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008
title_sort possible interruption of malaria transmission, highland kenya, 2007–2008
publisher Centers for Disease Control and Prevention
series Emerging Infectious Diseases
issn 1080-6040
1080-6059
publishDate 2009-12-01
description Highland areas where malaria transmission is unstable are targets for malaria elimination because transmission decreases to low levels during the dry season. In highland areas of Kipsamoite and Kapsisiywa, Kenya (population ≈7,400 persons), annual household indoor residual spraying with a synthetic pyrethroid was performed starting in 2005, and artemether/lumefantrine was implemented as first-line malaria treatment in October 2006. During April 2007–March 2008, no microscopy-confirmed cases of malaria occurred at the sites. In 4 assessments of asymptomatic persons during May 2007–April 2008, a total of <0.3% of persons were positive for asexual Plasmodium falciparum by microscopy or PCR at any time, and none were positive by PCR at the last 2 sample collections. Our findings show that in such areas, interruption and eventual elimination of malaria transmission may be achievable with widespread annual indoor residual spraying of households and artemisinin combination therapy.
topic Malaria
transmission
Plasmodium falciparum
epidemiology
Kenya
parasites
url https://wwwnc.cdc.gov/eid/article/15/12/09-0627_article
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