Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008
Highland areas where malaria transmission is unstable are targets for malaria elimination because transmission decreases to low levels during the dry season. In highland areas of Kipsamoite and Kapsisiywa, Kenya (population ≈7,400 persons), annual household indoor residual spraying with a synthetic...
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Centers for Disease Control and Prevention
2009-12-01
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Series: | Emerging Infectious Diseases |
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Online Access: | https://wwwnc.cdc.gov/eid/article/15/12/09-0627_article |
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doaj-43173867fd3e4641a95dda22b0db18842020-11-24T21:50:07ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592009-12-0115121917192410.3201/eid1512.090627Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008Chandy C. JohnMelissa A. RiedeselNg’wena G. MagakKim A. LindbladeDavid M. MengeJames S. HodgesJohn M. VululeWillis AkhwaleHighland areas where malaria transmission is unstable are targets for malaria elimination because transmission decreases to low levels during the dry season. In highland areas of Kipsamoite and Kapsisiywa, Kenya (population ≈7,400 persons), annual household indoor residual spraying with a synthetic pyrethroid was performed starting in 2005, and artemether/lumefantrine was implemented as first-line malaria treatment in October 2006. During April 2007–March 2008, no microscopy-confirmed cases of malaria occurred at the sites. In 4 assessments of asymptomatic persons during May 2007–April 2008, a total of <0.3% of persons were positive for asexual Plasmodium falciparum by microscopy or PCR at any time, and none were positive by PCR at the last 2 sample collections. Our findings show that in such areas, interruption and eventual elimination of malaria transmission may be achievable with widespread annual indoor residual spraying of households and artemisinin combination therapy.https://wwwnc.cdc.gov/eid/article/15/12/09-0627_articleMalariatransmissionPlasmodium falciparumepidemiologyKenyaparasites |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chandy C. John Melissa A. Riedesel Ng’wena G. Magak Kim A. Lindblade David M. Menge James S. Hodges John M. Vulule Willis Akhwale |
spellingShingle |
Chandy C. John Melissa A. Riedesel Ng’wena G. Magak Kim A. Lindblade David M. Menge James S. Hodges John M. Vulule Willis Akhwale Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008 Emerging Infectious Diseases Malaria transmission Plasmodium falciparum epidemiology Kenya parasites |
author_facet |
Chandy C. John Melissa A. Riedesel Ng’wena G. Magak Kim A. Lindblade David M. Menge James S. Hodges John M. Vulule Willis Akhwale |
author_sort |
Chandy C. John |
title |
Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008 |
title_short |
Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008 |
title_full |
Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008 |
title_fullStr |
Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008 |
title_full_unstemmed |
Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008 |
title_sort |
possible interruption of malaria transmission, highland kenya, 2007–2008 |
publisher |
Centers for Disease Control and Prevention |
series |
Emerging Infectious Diseases |
issn |
1080-6040 1080-6059 |
publishDate |
2009-12-01 |
description |
Highland areas where malaria transmission is unstable are targets for malaria elimination because transmission decreases to low levels during the dry season. In highland areas of Kipsamoite and Kapsisiywa, Kenya (population ≈7,400 persons), annual household indoor residual spraying with a synthetic pyrethroid was performed starting in 2005, and artemether/lumefantrine was implemented as first-line malaria treatment in October 2006. During April 2007–March 2008, no microscopy-confirmed cases of malaria occurred at the sites. In 4 assessments of asymptomatic persons during May 2007–April 2008, a total of <0.3% of persons were positive for asexual Plasmodium falciparum by microscopy or PCR at any time, and none were positive by PCR at the last 2 sample collections. Our findings show that in such areas, interruption and eventual elimination of malaria transmission may be achievable with widespread annual indoor residual spraying of households and artemisinin combination therapy. |
topic |
Malaria transmission Plasmodium falciparum epidemiology Kenya parasites |
url |
https://wwwnc.cdc.gov/eid/article/15/12/09-0627_article |
work_keys_str_mv |
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1725885165394198528 |