Rapid detection of colistin resistance protein MCR-1 by LC–MS/MS

Abstract Background Colistin (polymyxin E) and polymixin B are important bactericidal antibiotics used in the treatment of serious infections caused by multi-drug resistant Gram-negative organisms. Transferrable plasmid-mediated colistin resistance, conferred by the product of the mcr-1 gene, has em...

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Bibliographic Details
Main Authors: Honghui Wang, Yong Chen, Jeffrey R. Strich, Steven K. Drake, Jung-Ho Youn, Avi Z. Rosenberg, Marjan Gucek, Patrick T. McGann, Anthony F. Suffredini, John P. Dekker
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Clinical Proteomics
Online Access:http://link.springer.com/article/10.1186/s12014-019-9228-2