Assessment of humoral immune responses to blood-stage malaria antigens following ChAd63-MVA immunization, controlled human malaria infection and natural exposure.

The development of protective vaccines against many difficult infectious pathogens will necessitate the induction of effective antibody responses. Here we assess humoral immune responses against two antigens from the blood-stage merozoite of the Plasmodium falciparum human malaria parasite--MSP1 and...

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Main Authors: Sumi Biswas, Prateek Choudhary, Sean C Elias, Kazutoyo Miura, Kathryn H Milne, Simone C de Cassan, Katharine A Collins, Fenella D Halstead, Carly M Bliss, Katie J Ewer, Faith H Osier, Susanne H Hodgson, Christopher J A Duncan, Geraldine A O'Hara, Carole A Long, Adrian V S Hill, Simon J Draper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4177865?pdf=render