TP53 p.Arg337His geographic distribution correlates with adrenocortical tumor occurrence

Abstract Background The p.Arg337His mutation of the TP53 is the most frequent germline missense variant associated with cancer described so far in this gene. It is mainly found in the South and Southeastern regions of Brazil, where it has been associated with a high incidence of pediatric adrenocort...

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Bibliographic Details
Main Authors: Ana L. Seidinger, Isabel P. Caminha, Maria J. Mastellaro, Carmen S. Gabetta, Alexandre E. Nowill, Vitória R. P. Pinheiro, José A. Yunes
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
Online Access:https://doi.org/10.1002/mgg3.1168