Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness.

Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness.

Merkel cell carcinoma (MCC) is an aggressive skin cancer with a high propensity for recurrence and metastasis. Merkel cell polyomavirus (MCPyV) is recognised as the causative factor in the majority of MCC cases. The MCPyV small tumour antigen (ST) is considered to be the main viral transforming fact...

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Bibliographic Details
Main Authors: Nnenna Nwogu, James R Boyne, Samuel J Dobson, Krzysztof Poterlowicz, G Eric Blair, Andrew Macdonald, Jamel Mankouri, Adrian Whitehouse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007276

Internet

https://doi.org/10.1371/journal.ppat.1007276

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