Selection and application of ssDNA aptamers to detect active TB from sputum samples.

BACKGROUND: Despite the enormous global burden of tuberculosis (TB), conventional approaches to diagnosis continue to rely on tests that have major drawbacks. The improvement of TB diagnostics relies, not only on good biomarkers, but also upon accurate detection methodologies. The 10-kDa culture fil...

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Bibliographic Details
Main Authors: Lia S Rotherham, Charlotte Maserumule, Keertan Dheda, Jacques Theron, Makobetsa Khati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3464247?pdf=render