Rapid biodegradable microneedles with allergen reservoir for skin allergy test
Abstract With the increasing allergy cases worldwide, this study introduces a biodegradable microneedle system to facilitate allergy testing process. Dissolving microneedle provides a minimally invasive manner to go through skin barrier while avoiding needle phobia among patents, especially children...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2020-07-01
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| Series: | Micro and Nano Systems Letters |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40486-020-00114-z |
| Summary: | Abstract With the increasing allergy cases worldwide, this study introduces a biodegradable microneedle system to facilitate allergy testing process. Dissolving microneedle provides a minimally invasive manner to go through skin barrier while avoiding needle phobia among patents, especially children. The microneedles were fabricated using copolymer polyvinylpyrrolidone-co-methacrylic acid (PVP-MAA) material. To ensure the successful insertion of microneedles into the skin, we tailored the mechanical strength of the copolymer by adjusting the weight ratio of two constituted polymers. A reservoir was designed to load allergy specimen for the allergy test. This system is expected to offer a simple and effective allergy testing that can facilitate the allergy testing protocol. |
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| ISSN: | 2213-9621 |