Transplantation of hMSCs Genome Edited with LEF1 Improves Cardio-Protective Effects in Myocardial Infarction

Stem cell-based therapy is one of the most attractive approaches to ischemic heart diseases, such as myocardial infarction (MI). We evaluated the cardio-protective effects of the human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) stably expressing lymphoid enhancer-binding factor...

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Bibliographic Details
Main Authors: Hyun-Min Cho, Kang-Hoon Lee, Yi-ming Shen, Tae-Jin Shin, Pan-Dong Ryu, Min-Cheol Choi, Kyung-Sun Kang, Je-Yoel Cho
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120300421