Novel Combination of COX-2 Inhibitor and Antioxidant Therapy for Modulating Oxidative Stress Associated with Intestinal Ischemic Reperfusion Injury and Endotoxemia

Novel Combination of COX-2 Inhibitor and Antioxidant Therapy for Modulating Oxidative Stress Associated with Intestinal Ischemic Reperfusion Injury and Endotoxemia

Background: Intestinal ischemic reperfusion (I/R) injury is associated with a high mortality rate; this condition is also related to significant endotoxemia and systemic inflammation. The preservation of tissue perfusion and a sufficient blood flow are required to deliver nutrients and oxygen, prese...

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Bibliographic Details
Main Authors: Enrico Gugliandolo, Marika Cordaro, Rosalba Siracusa, Ramona D’Amico, Alessio Filippo Peritore, Tiziana Genovese, Daniela Impellizzeri, Rosanna Di Paola, Rosalia Crupi, Salvatore Cuzzocrea, Roberta Fusco
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Antioxidants
Subjects:
intestinal strangulation
antioxidant
Online Access:https://www.mdpi.com/2076-3921/9/10/930

Internet

https://www.mdpi.com/2076-3921/9/10/930

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