Early-onset preeclampsia predisposes to preclinical diastolic left ventricular dysfunction in the fifth decade of life: An observational study.

Early-onset preeclampsia predisposes to preclinical diastolic left ventricular dysfunction in the fifth decade of life: An observational study.

BACKGROUND:Systemic inflammation, endothelial dysfunction and deficient vascularization of either uterus or myocardium are mechanistic hallmarks of early-onset preeclampsia and heart failure with preserved ejection fraction (HFpEF). HFpEF is especially prevalent in elderly women and preceded in midd...

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Main Authors: Anouk Bokslag, Constantijn Franssen, Lisa J Alma, Igor Kovacevic, Floortje van Kesteren, Pim W Teunissen, Otto Kamp, Wessel Ganzevoort, Peter L Hordijk, Christianne J M de Groot, Walter J Paulus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5997308?pdf=render

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http://europepmc.org/articles/PMC5997308?pdf=render

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