Nanoporous Microneedle Arrays Effectively Induce Antibody Responses against Diphtheria and Tetanus Toxoid

Nanoporous Microneedle Arrays Effectively Induce Antibody Responses against Diphtheria and Tetanus Toxoid

The skin is immunologically very potent because of the high number of antigen-presenting cells in the dermis and epidermis, and is therefore considered to be very suitable for vaccination. However, the skin’s physical barrier, the stratum corneum, prevents foreign substances, including vaccines, fro...

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Bibliographic Details
Main Authors: Anne Marit de Groot, Anouk C. M. Platteel, Nico Kuijt, Peter J. S. van Kooten, Pieter Jan Vos, Alice J. A. M. Sijts, Koen van der Maaden
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
nanoporous microneedles
intradermal vaccination
antigen release
humoral immune response
diphtheria
tetanus
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01789/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01789/full

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