The nasal methylome as a biomarker of asthma and airway inflammation in children

Epigenetic differences in nasal epithelium have been proposed as a biomarker for lower airway disease and asthma. Here, in epigenome-wide association studies for asthma and other airway traits using nasal swabs, the authors identify differentially methylated CpGs that highlight genes involved in TH2...

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Bibliographic Details
Main Authors: Andres Cardenas, Joanne E. Sordillo, Sheryl L. Rifas-Shiman, Wonil Chung, Liming Liang, Brent A. Coull, Marie-France Hivert, Peggy S. Lai, Erick Forno, Juan C. Celedón, Augusto A. Litonjua, Kasey J. Brennan, Dawn L. DeMeo, Andrea A. Baccarelli, Emily Oken, Diane R. Gold
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11058-3