Mechanisms of Perceived Treatment Assignment and Subsequent Expectancy Effects in a Double Blind Placebo Controlled RCT of Major Depression

Mechanisms of Perceived Treatment Assignment and Subsequent Expectancy Effects in a Double Blind Placebo Controlled RCT of Major Depression

Objective: It has been suggested that patients' perception of treatment assignment might serve to bias results of double blind randomized controlled trials (RCT). Most previous evidence on the effects of patients' perceptions and the mechanisms influencing these perceptions relies on cross...

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Bibliographic Details
Main Authors: Johannes A. C. Laferton, Sagar Vijapura, Lee Baer, Alisabet J. Clain, Abigail Cooper, George Papakostas, Lawrence H. Price, Linda L. Carpenter, Audrey R. Tyrka, Maurizio Fava, David Mischoulon
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Psychiatry
Subjects:
major depressive disorder
SAMe
escitalopram
placebo
perceived treatment assignment
un-blinding
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00424/full

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https://www.frontiersin.org/article/10.3389/fpsyt.2018.00424/full

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