Pancreatic transcription factors containing protein transduction domains drive mouse embryonic stem cells towards endocrine pancreas.
Protein transduction domains (PTDs), such as the HIV1-TAT peptide, have been previously used to promote the uptake of proteins into a range of cell types, including stem cells. Here we generated pancreatic transcription factors containing PTD sequences and administered these to endoderm enriched mou...
Main Authors: | Maria João Lima, Hilary M Docherty, Yuanxiao Chen, Ludovic Vallier, Kevin Docherty |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3341374?pdf=render |
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