Transcriptional Alterations by Ischaemic Postconditioning in a Pig Infarction Model: Impact on Microvascular Protection

Transcriptional Alterations by Ischaemic Postconditioning in a Pig Infarction Model: Impact on Microvascular Protection

Although the application of cardioprotective ischaemia/reperfusion (I/R) stimuli after myocardial infarction (MI) is a promising concept for salvaging the myocardium, translation to a clinical scenario has not fulfilled expectations. We have previously shown that in pigs, ischaemic postconditioning...

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Bibliographic Details
Main Authors: Dominika Lukovic, Alfred Gugerell, Katrin Zlabinger, Johannes Winkler, Noemi Pavo, Tamás Baranyai, Zoltán Giricz, Zoltán V. Varga, Martin Riesenhuber, Andreas Spannbauer, Denise Traxler, András Jakab, Rita Garamvölgyi, Örs Petnehazy, Dietmar Pils, Levente Tóth, Rainer Schulz, Péter Ferdinandy, Mariann Gyöngyösi
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
ischemia-reperfusion injury
acute myocardial infarction
ischemic postconditioning
transcriptome
porcine model
Online Access:http://www.mdpi.com/1422-0067/20/2/344

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