Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat
<p>Abstract</p> <p>Background</p> <p>Cerebral ischemia is usually characterized by a reduction in local blood flow and metabolism and by disruption of the blood-brain barrier in the infarct region. The formation of oedema and opening of the blood-brain barrier in stroke...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-06-01
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Series: | BMC Neuroscience |
Online Access: | http://www.biomedcentral.com/1471-2202/10/56 |