Immune protection against Trypanosoma cruzi induced by TcVac4 in a canine model.

Immune protection against Trypanosoma cruzi induced by TcVac4 in a canine model.

Chagas disease, caused by Trypanosoma cruzi, is endemic in southern parts of the American continent. Herein, we have tested the protective efficacy of a DNA-prime/T. rangeli-boost (TcVac4) vaccine in a dog (Canis familiaris) model. Dogs were immunized with two-doses of DNA vaccine (pcDNA3.1 encoding...

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Bibliographic Details
Main Authors: José E Aparicio-Burgos, José A Zepeda-Escobar, Roberto Montes de Oca-Jimenez, José G Estrada-Franco, Alberto Barbabosa-Pliego, Laucel Ochoa-García, Ricardo Alejandre-Aguilar, Nancy Rivas, Giovanna Peñuelas-Rivas, Margarita Val-Arreola, Shivali Gupta, Felix Salazar-García, Nisha J Garg, Juan C Vázquez-Chagoyán
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4390229?pdf=render

Internet

http://europepmc.org/articles/PMC4390229?pdf=render

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