Administration of Higher Doses of Amikacin in Early Stages of Sepsis in Critically Ill Patients

Administration of Higher Doses of Amikacin in Early Stages of Sepsis in Critically Ill Patients

High-dose extended-interval dosage (HDED) regimen of aminoglycosides is now considered as the standard dosage strategy in sepsis. Although safety and efficacy of this dosing regimen is well studied, but new experiments show increased the risk of resistance development associated with %T>MIC less...

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Bibliographic Details
Main Authors: Farhad Najmeddin, Arezoo Ahmadi, Laleh Mahmoudi, Kourosh Sadeghi, Hossein Khalili, Alireza Ahmadvand, Atabak Najafi, Mojtaba Mojtahedzadeh
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2014-09-01
Series:Acta Medica Iranica
Subjects:
Amikacin
High dose
extended interval dosage
Moderate dose
non liberal interval dosage
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/4657

Internet

https://acta.tums.ac.ir/index.php/acta/article/view/4657

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