Enhanced mitophagy in bronchial fibroblasts from severe asthmatic patients.

<h4>Background</h4>Sub-epithelial fibrosis is a characteristic feature of airway remodeling in asthma which correlates with disease severity. Current asthma medications are ineffective in treating fibrosis. In this study, we aimed to investigate the mitochondrial phenotype in fibroblasts...

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Bibliographic Details
Main Authors: Rakhee K Ramakrishnan, Khuloud Bajbouj, Mahmood Y Hachim, Andrea K Mogas, Bassam Mahboub, Ronald Olivenstein, Rifat Hamoudi, Rabih Halwani, Qutayba Hamid
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242695