%0 Article %A Suneesh Kumar Pachathundikandi %I Nature Publishing Group %D 2019 %G English %B Nature Communications %@ 2041-1723 %T T4SS-dependent TLR5 activation by Helicobacter pylori infection %U https://doi.org/10.1038/s41467-019-13506-6 %X Toll-like receptor TLR5 recognizes a domain, D1, that is present in flagellins of several pathogenic bacteria but not in Helicobacter pylori. Here, the authors show that TLR5 can be activated independently of flagellin by a component of the H. pylori type IV secretion system that contains a D1-like motif.