Postural Body Sway as Surrogate Outcome for Myelopathy in Adrenoleukodystrophy

Postural Body Sway as Surrogate Outcome for Myelopathy in Adrenoleukodystrophy

BackgroundMyelopathy is the core clinical manifestation of adrenoleukodystrophy (ALD), which is the most common peroxisomal disorder. Development of therapies requires sensitive and clinically relevant outcome measures. Together with spastic paraparesis, balance disturbance is the main cause of disa...

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Bibliographic Details
Main Authors: Wouter J. C. van Ballegoij, Stephanie I. W. van de Stadt, Irene C. Huffnagel, Stephan Kemp, Marjo S. van der Knaap, Marc Engelen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Physiology
Subjects:
X-linked adrenoleukodystrophy
myelopathy
spinal cord
balance
body sway
surrogate outcome
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00786/full

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